ABSTRACT

Gastric carcinoma, a significant global health concern, continues to present clinical challenges due to its diverse biological behavior and variable outcomes. We aimed to provide a comprehensive analysis of the intricate relationship between tumor diameter and mitotic index in gastric carcinoma. A total of 30 patients who were followed up with a diagnosis of gastric carcinoma and died in our clinic in the last ten years were included in the study. Tumor age and mitotic index information of these patients were obtained by retrospectively scanning the hospital records. The mean age of the patients was 57.7 years. 17 of the patients (56.5%) were male. The mean survival time was 62.1 (28.2) months. There was no difference in mean survival between genders (p=0.412). The mean survival time in patients with a tumor diameter of more than 5 centimeters was significantly lower than in those with a tumor diameter of 5 cm or less (p = 0.011). The mean survival time in those with a mitotic index above 5/50 HPF was found to be significantly lower than in the group with 5/50 HPF and below (p=0.018). Our comprehensive examination of prognostic factors in gastric carcinoma has revealed significant associations between tumor characteristics and patient outcomes. The substantial differences in mean survival times based on tumor diameter and mitotic index underscore the critical roles these factors play in shaping the disease trajectory.

Keywords

Gastric carcinoma, tumor size, mitotic index, survival.

MJE-003